From Knowledge Sharing to Collective Intelligence
In complex scientific environments, no single actor holds all the answers. The true value lies in ecosystems with cross-disciplinary knowledge, shared learnings, and iterative feedback that build a more comprehensive understanding of the challenges we face.Platforms...
Data Density and Chemical Reproducibility: Ensuring Consistency in Process Optimization
Reproducibility is one of the most overlooked aspects in the world of process optimization. As we increasingly rely on data-rich experimentation, like Design of Experiments (DoE), in-line monitoring, and real-time analytics, ensuring data consistency and traceability...
From Molecule to Manufacture: Scaling as a Design Constraint
In industrial chemistry, scalability isn’t something that should be considered later in the process. In fact it must be a primary design parameter from the very start.When reactions are optimized without considering the realities of equipment or the constraints of...
Retrofitting Batch Mindsets in Continuous Environments: A Paradigm Shift
Transitioning from batch to continuous processes is often perceived as a technical challenge. But in reality, the most significant barrier isn’t the technology, it’s the mindset.Teams that have spent years mastering batch operations often find themselves transferring...
Green Metrics vs. Green Reality: A Holistic Approach to Sustainability in Synthesis
Metrics like atom economy and the E-factor have become foundational tools for evaluating sustainability in chemical synthesis. But do they tell the whole story?While these metrics provide useful insights, they often lack critical context:🧪Reagent Availability: How...
KPIs in Process Chemistry: The Cost of What We Don’t Measure
In chemical process development, the term "success" often gets reduced to two metrics: yield and selectivity. And while those are important, they offer only a partial view of process performance.But what about:🔁 Reproducibility across batches and operators?⚡ Energy...
Catalysis and Sustainability: Beyond the Reaction Vessel
When we talk about “green catalysis,” the conversation often stops at milder conditions or improved yields. But the true environmental impact of catalysis goes far beyond the reaction vessel.A catalyst may enable lower temperatures or faster conversions, but that’s...
AI in Chemistry: Between Data Abundance and Lack of Decision
Artificial Intelligence is transforming chemistry (there’s no doubt).From retrosynthetic route generation to NMR pattern recognition, reaction optimization to automated literature mining, the breadth of applications is growing daily.But in our experience, the real...
Rethinking Flow Chemistry: Infrastructure or Mindset?
In many industrial contexts, flow chemistry is still perceived as an emerging or optional technology, usually something to “try out” when batch reaches its limits.But this perspective underestimates its true impact. Flow chemistry is not merely a tool. It represents a...
The future of chemistry: Smarter, Greener, Faster
🌿🔬 Drive Sustainability and Innovation Forward with Alza & Associates 🔬🌿At Alza & Associates, we're committed to pioneering sustainable solutions through advanced chemistry, novel technologies, automatization and artificial intelligence (AI). With our deep...
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LinkedIn links below to get in touch.
Miquel A. Pericàs
Founding Director of Institute of Chemical Research of Catalonia
Alza & Associates
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Esther Alza
Co-Founder @ A&A Sustainable Chemistry
Alza & Associates
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